Nanofluidic devices for the separation of biomolecules,
Chathurika Rathnayaka, Charuni A. Amarasekara, Khurshed Akabirov, Michael C. Murphy, Sunggook Park, Malgorzata A. Witek, Steven A. Soper, Journal of Chromatography A, Volume 1683, 2022, Doi: 10.1016/j.chroma.2022.463539. PMCID:
Electrical Characteristics of Individual FeNiCo-Au Core-Shell Nanowires Integrated into Microelectrodes on Plastic Substrate M Beheshti, X Geng, J Choi, E Podlaha-Murphy, S Park TechConnect Briefs (Proceedings of Nanotech 18 Conference), Vol. 1 (2018) 172-175. (ISBN 978-0-9988782-2-5).
Polymer-based Nanosensors using Flight-Time Identification of Mononucleotides for Single-Molecule Sequencing SA Soper, S Park, E Podlaha-Murphy Abstracts of Papers of the American Chemical Society 2017, 254
Fabrication of Nanopores in Polymer Membranes using Nanoimprint Lithography for DNA Analysis
J Choi, S Park 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), October 25-29, 2015, Gyongju, Korea, Pages 1112-1114.
Our team of senior scientists from KU, KU Medical Center, UNC, Wake Forest Medical School, and LSU aims to design, manufacture and deliver new tools to the biomedical community for analyzing circulating biomarkers for disease management. These circulating biomarkers comprise a Liquid Biopsy, which can be secured from blood, urine, cerebrospinal fluid or others. These markers come in many forms as well, such as whole biological cells, cell free molecules, cell free DNA, and extracellular vesicles, exosomes.
The tools we are developing consist of devices across many different length scales that provide the ability to enrich these markers from clinical samples and then, analyze them by genotyping and sequencing the DNA/RNA content of these markers. The technology we are pioneering is highly conducive to translation into the clinical laboratory.
University of Kansas
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Lawrence, KS 66045